Dr. Rajesh Singh

FACULTY OF SCIENCE >> Department of Bio-Chemistry
 
Designation : Professor
Qualification : MSc. Goa University, Goa, India Ph.D. (SG Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, UP, India)
Phone Nos : 912652795594
Email :
Experience : Post-doctoral fellow at NIEHS/NIH, NC, USA and Thomas Jefferson University, Philadelphia. , Marie Curie More Experienced Researcher NUI, Galway, Ireland , Independent Researcher at Indian Institute of Advanced Research, Gandhinagar, Gujarat, India
Areas of Interest : The role of ubiquitin E3 ligases in regulation of cross talk of autophagy and cell death and its role in mitochondrial metabolism., The spatio-temporal regulation of miRNA and its role in mitochondrial function and cell death., Ubiquitin and mitochondrial crosstalk during S. aureus infection in human epithelial cells
 
Dr. Rajesh Singh

Detailed CV

Name: Dr. Rajesh Singh
Designation: Associate Professor
Contact:  Singhraj1975@gmail.com
Academic background:
 
Graduation:  Lucknow University, 1994                           
                                                           
Postgradaution: Goa University, 1996               
 
Ph.D.               SG Post Graduate        2002                Mol Endocrinology
                        Institute of Med Sc
 
Professional experience:
 
05/2002-10/2002   Postdoc Fellow at NIEHS/NIH, NC, USA
10/2002 -05/2006  Post-doctoral fellow at Center for Apoptosis Research, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia.
11/2007-02/2008   Marie Curie More Experienced Researcher at National University of Ireland, Galway, Ireland
07/2006-08/2013   Assistant professor and Group Leader at Indian Institute of Advanced Research, Gandhinagar, Gujarat, India
08/2013-Present    Associate Professor
                            Department of Biochemistry
                            The MS University of Baroda

 
 Research interests:
 
  1. Study the role of mitochondria in regulation of inflammation during cancer and neurodegneration.
  2. Role of Ub E3 Ligases in regulation of inflammation and metabolism
  3. Study the spatio temporal regulation of miRNA:Special focus on Mitochondria
  4. Role of mitochondrial biogenesis during S. aureus infection
 
 
 List of recent publications:
 
  1.  Tomar D, Singh R, Singh AK, Pandya CD, Singh R*. TRIM13 regulates ER stress induced autophagy and clonogenic ability of the cells. Biochim Biophys Acta. (Mol Cell Res) 2011 Dec 8;1823(2):316-326. [Epub ahead of print]
 
 
  1. Singh AK, Singh R, Tomar D, Pandya CD, Singh R* (2012) The Leucine aminopeptidase of Staphylococcus aureus is secreted and contributes to biofilm formation. Int J Infect Dis. 2012 May;16(5):e375-81. Epub 2012 Mar 10.
 
  1. Sripada L, Tomar D, Prajapati P, Singh R, Singh AK, Singh R* (2012) Systematic Analysis of Small RNAs Associated with Human Mitochondria by Deep Sequencing: Detailed Analysis of Mitochondrial Associated miRNA. PLoS ONE 7(9): e44873. doi:10.1371/journal.pone.0044873
 
  1. Tomar D Prajapati P, Sripada L, Singh R, Singh AK, Singh R* (2012) Nucleo-cytoplasmic trafficking of TRIM8, a novel oncogene, is involved in positive regulation of TNF induced NF-κB pathway. PLoS One 2012;7(11):e48662. doi: 10.1371/journal.pone.0048662. Epub 2012 Nov 12
 
  1. Sripada L, Tomar D, Singh R* (2012). Mitochondria: One of the destination of miRNA. Mitochondrion Nov;12(6):593-9. doi: 10.1016/j.mito.2012.10.009. Epub 2012 Oct 17.
 
  1. Tomar D Prajapati P, Sripada L, Singh R, Singh AK, Singh R* (2013)TRIM13 regulates caspase-8 ubiquitination, translocation to autophagosomes and activation during ER stress induced cell death. Biochim Biophys Acta. 2013 Sep 8;1833(12):3134-3144.
 
  1. Rajpara N, Vinothkumar K, Mohanty P, Singh AK, Singh R, Sinha R, Nag D, Koley H, Kushwaha Bhardwaj A. Synergistic effect of various virulence factors leading to high toxicity of environmental V. cholerae non-O1/ non-O139 isolates lacking ctx gene : comparative study with clinical strains. PLoS One. 2013 Sep 23;8(9):e76200. doi: 10.1371/journal.pone.0076200.
 
  1. Singh R, Sripada L, Singh R* (2013) "Side effects of antibiotics during bacterial infections: Mitochondria, the main target in host cell. Mitochondrion Nov 16. pii: S1567-7249(13)00270-5. doi: 10.1016/j.mito.2013.10.005. [Epub ahead of print]
 
  1. Bhatelia K, Singh A, TomarD , Singh K, Sripada L, Chagtoo M, Prajapati P, Singh R, Godbole MM, Singh R* (2014) Antiviral signaling protein MITA act as a tumor suppressor in breast cancer by regulating NF-κB induced cell death. BBA, Mol Basis of Diseases Feb;1842(2):144-53. doi: 10.1016/j.bbadis.2013.11.006. Epub 2013 Nov 13.
 
 
  • Contributed equally    * Corresponding author
 
 
 
Book Chapter:
 
TRIM13, Novel Tumor Supressor, Regulator of cosstalk of autophagy and cell death. Chapter Autophagy Vol (1): 2013
 
Courses being taught during 2013-2014:
Advanced Cell Biology
Cell Biology
 
Detailed Curriculum Vitae:
https://sites.google.com/site/rajeshsinghlabmsu/

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25-11-2016 17:32:58